Skip navigation

Dr Edwin Lasonder

Assistant Professor

Department: Applied Sciences

Edwin Lasonder

My research interests are developing mass spectrometry-based proteomics applications for studying human diseases such as malaria and cancers. Malaria remains one of the most lethal infectious diseases around the world and is caused by the Apicomplexan parasite Plasmodium falciparum. The life cycle of the parasite is complex and composed of several developmental stages in mosquito and human hosts. Throughout out my professional career I have used state-of-the art proteomic technologies to identify targets for intervention strategies at different stages of the parasite life cycle since the P falciparum genome was sequenced and was the first in publishing global proteomes of the human malaria parasite at various life cycle stages.  Since then I have been studying the biology of the parasite P. falciparum in human host for the development of novel intervention strategies using a variety of methods including expression profiling, post-translational modification (PTM) studies and protein-protein interaction network analyses. 

  • Please visit the Pure Research Information Portal for further information
  • cAMP-Dependent Signaling Pathways as Potential Targets for Inhibition of Plasmodium falciparum Blood Stages, Lasonder, E., More, K., Singh, S., Haidar, M., Bertinetti, D., Kennedy, E., Herberg, F., Holder, A., Langsley, G., Chitnis, C. 24 May 2021, In: Frontiers in Microbiology
  • NAD(P) transhydrogenase has vital non-mitochondrial functions in malaria parasite transmission, Saeed, S., Tremp, A., Sharma, V., Lasonder, E., Dessens, J. 4 Mar 2020, In: EMBO Reports
  • Plasmodium berghei LAPs form an extended protein complex that facilitates crystalloid targeting and biogenesis, Tremp, A., Saeed, S., Sharma, V., Lasonder, E., Dessens, J. 15 Sep 2020, In: Journal of Proteomics
  • Ubiquitin activation is essential for schizont maturation in Plasmodium falciparum blood-stage development, Green, J., Wu, Y., Encheva, V., Lasonder, E., Prommaban, A., Kunzelmann, S., Christodoulou, E., Grainger, M., Truongvan, N., Bothe, S., Sharma, V., Song, W., Pinzuti, I., Uthaipibull, C., Srichairatanakool, S., Birault, V., Langsley, G., Schindelin, H., Stieglitz, B., Snijders, A., Holder, A. 22 Jun 2020, In: PLoS Pathogens
  • Vesiculation of Red Blood Cells in the Blood Bank: A Multi-Omics Approach towards Identification of Causes and Consequences, Freitas Leal, J., Lasonder, E., Sharma, V., Schiller, J., Fanelli, G., Rinalducci, S., Brock, R., Bosman, G. 31 Mar 2020, In: Proteomes
  • Proteomic analysis discovers the differential expression of novel proteins and phosphoproteins in meningioma including NEK9, HK2 and SET and deregulation of RNA metabolism, Dunn, J., Ferluga, S., Sharma, V., Futschik, M., Hilton, D., Adams, C., Lasonder, E., Hanemann, C. 1 Feb 2019, In: EBioMedicine
  • Publisher Correction: Unravelling the immune signature of Plasmodium falciparum transmission-reducing immunity (Nature communications (2018) 9 1 (558)), Stone, W., Campo, J., Ouédraogo, A., Meerstein-Kessel, L., Morlais, I., Da, D., Cohuet, A., Nsango, S., Sutherland, C., van de Vegte-Bolmer, M., Siebelink-Stoter, R., van Gemert, G., Graumans, W., Lanke, K., Shandling, A., Pablo, J., Teng, A., Jones, S., de Jong, R., Fabra-García, A., Bradley, J., Roeffen, W., Lasonder, E., Gremo, G., Schwarzer, E., Janse, C., Singh, S., Theisen, M., Felgner, P., Marti, M., Drakeley, C., Sauerwein, R., Bousema, T., Jore, M. Dec 2018, In: Nature Communications
  • Unravelling the immune signature of Plasmodium falciparum transmission-reducing immunity, Stone, W., Campo, J., Ouédraogo, A., Meerstein-Kessel, L., Morlais, I., Da, D., Cohuet, A., Nsango, S., Sutherland, C., Van De Vegte-Bolmer, M., Siebelink-Stoter, R., Van Gemert, G., Graumans, W., Lanke, K., Shandling, A., Pablo, J., Teng, A., Jones, S., De Jong, R., Fabra-García, A., Bradley, J., Roeffen, W., Lasonder, E., Gremo, G., Schwarzer, E., Janse, C., Singh, S., Theisen, M., Felgner, P., Marti, M., Drakeley, C., Sauerwein, R., Bousema, T., Jore, M. 1 Dec 2018, In: Nature Communications
  • Clinical proteomics: From biological sample to clinical exploitation, Lasonder, E. 1 Jun 2017, In: Proteomes
  • Global Proteome and Phospho-proteome Analysis of Merlin-deficient Meningioma and Schwannoma Identifies PDLIM2 as a Novel Therapeutic Target, Bassiri, K., Ferluga, S., Sharma, V., Syed, N., Adams, C., Lasonder, E., Hanemann, C. 1 Feb 2017, In: EBioMedicine

  • Microbiology PhD November 15 1995
  • Fellow (FHEA) Higher Education Academy (HEA) 2020


a sign in front of a crowd
+

Northumbria Open Days

Open Days are a great way for you to get a feel of the University, the city of Newcastle upon Tyne and the course(s) you are interested in.

Research at Northumbria
+

Research at Northumbria

Research is the life blood of a University and at Northumbria University we pride ourselves on research that makes a difference; research that has application and affects people's lives.

NU World
+

Explore NU World

Find out what life here is all about. From studying to socialising, term time to downtime, we’ve got it covered.


Latest News and Features

academic Jennifer Aston pictured in a law library holding an open book
Launch of The Regeneration Shop in Chopwell. Sarah Cotton, Senior Programmes Manager at Chopwell Regeneration Group; Jennine Wilson, Lecturer in Fashion and Senior Technician at Northumbria University; Hal Convery, Shop Manager at The Regeneration Shop; Crystal Hicks, Executive Director of Chopwell Regeneration Group; Gayle Cantrell, Assistant Professor BA Fashion Communication at Northumbria University; Sophie Wetherell, Assistant Professor BA Fashion / MA Fashion Design at Northumbria University; Emma Jane Goldsmith Assistant Professor BA Fashion / MA Fashion Design at Northumbria University; Professor Anne Peirson-Smith, Head of Fashion at Northumbria University.
Mooting
A new toolkit has been developed to support rural communities with the development of renewable energy projects. Photo: Adobe Stock
From left to right: Natalie Winchester, Subject Lead Health and Social Care and Post-16 Raising Standard Leader at Bede Academy, Dr Julie Derbyshire – Director of Apprenticeships and Assistant Professor in Nursing at Northumbria University, Andrew Thelwell – Principal at Bede Academy, Professor Alison Machin, Head of Department of Nursing, Midwifery and Health at Northumbria University and pupils from Bede Academy.
British Military Uniform
More news

Back to top