AP0404 - Cell Biology and Genetics

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What will I learn on this module?

You will learn about basics of the diversity of life and the unifying cell theory including, DNA as the universal information store and the central dogma of molecular biology as the unifying mechanism in all life. You will learn the structure and function of cells and the organelles they contain along with their life cycle, division, self-replication and eventual death.

You will learn the basic principles of heredity, including molecular, classical , human and microbial genetics. You will learn the structure, function, regulation of genes and genomes. You will also learn the fundamentals of applied genetics including an introduction to clinical genetics and the identification of genetic mutations and polymorphisms and their influence on disease processes.

Underpinning these theoretical concepts and principles covered in the lecture course you will be trained in basic techniques of handling DNA in the laboratory.

How will I learn on this module?

You will learn through lectures, seminars and laboratory practical sessions. The lectures will cover the theories and the concepts that will enable you to tackle complex genetic diseases and clinical cases presented in seminars and DNA manipulation in the practical.

How will I be supported academically on this module?

You will be given lecture materials and directed reading to inform both self-directed learning and in-class activities. Support will include self-test MCQ quizzes to provide formative feedback, allowing students to gauge their own performance prior to assessments. The module will make use of the eLP (Blackboard Ultra site) to provide content for pre reading and as a way of providing formative (practice) and summative assessment (marked). Staff will deal with your questions and queries in lectures and practical sessions on issues of module content and also to provide guidance on assessments and directed reading

What will I be expected to read on this module?

All modules at Northumbria include a range of reading materials that students are expected to engage with. The reading list for this module can be found at: http://readinglists.northumbria.ac.uk
(Reading List service online guide for academic staff this containing contact details for the Reading List team – http://library.northumbria.ac.uk/readinglists)

What will I be expected to achieve?

Knowledge & Understanding:
1. Understand the structure and function of the principal components and organelles of mammalian cells and microbes.
2. Understand the significance of nucleic acids and the Central dogma of molecular biology.
3. Describe structural, organisational and functional aspects of bacterial and human genes and genomes.
4. Interpret and solve problems based on chromosomal disorders or Mendelian genetics.

Intellectual / Professional skills & abilities:
5. An ability to conceive of processes at the molecular, cellular and cross generation (heritable) levels

Personal Values Attributes (Global / Cultural awareness, Ethics, Curiosity) (PVA):

How will I be assessed?

You will be formatively assessed with practice MCQ banks and feedback provided online.

You will be summatively assessed by two online assessments worth 50% each. The assessments will be composed of multiple choice questions (MCQs) and short answer questions (SAQs) testing Module Learning Outcomes 1-5

Pre-requisite(s)

N/A

Co-requisite(s)

N/A

Module abstract

You will study Cell biology; the structure and function of cells and the organelles they contain. This study includes their life cycle, division, self-replication and death processes. You will develop this knowledge further with the study of Genetics and molecular biology. In Genetics you will study the structure and function of genes and genomes. The Molecular Biology that underpins the manipulation of nucleic acids (DNA, RNA) will form the basis of a lectured material and a practical session. This introduces DNA manipulation and study in the laboratory.
You will then extend this knowledge into the study of the role of genes and mutations in inheritance of disease. This will introduced Clinical Genetics with the identification of genetic mutations and polymorphisms and their influence on disease processes are discussed.

Course info

Credits 20

Level of Study Undergraduate

Mode of Study four or five years depending on point of entry

Department Applied Sciences

Location Ellison Building, Newcastle City Campus

City Newcastle

Start September 2019

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